cryo-EM
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Programming virus capsid shape with DNA origami to tailor cargo protection
DNA-origami templates program viral coat proteins to assemble capsids with defined shapes, delivering nuclease-resistant, serum-stable cargo…
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Producing Mayaro virus-like particles with native glycoprotein assembly to de-risk vaccine design
Native-like Mayaro virus–like particles produced in mammalian cells elicit strong neutralizing antibodies and protect mice without…
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Mapping neutralizing antibody epitopes on AAV9 to guide variant design
Pre-existing neutralizing antibodies can limit who is eligible for AAV9 gene therapy and complicate re-dosing. Teams…
Nanometria 